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Eli Lilly did not immediately respond to Business Insider's request for comment

Semaglutides composition-of-matter patent is approaching expiry discussions in major markets, and there are generic manufacturers whove been preparing for this

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For instance, in December 2024, the U.S

Retatrutide is an investigational triple receptor agonist targeting GLP-1, GIP, and glucagon receptors, not yet licensed by the MHRA or EMA, and currently in Phase 2 and Phase 3 clinical trials