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Blood pressure and heart rate should be monitored at each visit, particularly during dose titration phases

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Additionally, individuals with a history of heart disease, high blood pressure, or diabetes should be particularly vigilant about any new or unusual chest pain

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Importantly, newer gene-profiling data suggest that GHK can influence the activity of a large number of human genes involved in stress response, repair, antioxidant defense, and regeneration, helping explain how one small peptide can produce such diverse benefits