NLRP3: Nod-like receptor protein 3
When combined with medications that also affect serotonin, there is a risk of developing serotonin syndrome
Several malignancies have been associated with alemtuzumab use in RRMS, including stage 1 thyroid papillary carcinoma with onset 1041 months from the last infusion, basal cell carcinoma, breast cancer, melanoma, non-EBV-associated Burkitt' s lymphoma, and Castleman disease
GFR decreases with age and renal disease, and is higher in men, pregnant women, and some disease states (eg, diabetes, obesity) (Rosner 2006
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Surprisingly, there was no overall reduction in stroke (HR 0.96