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In addition to gravitational loading, bone homeostasis is profoundly influenced by dynamic mechanical forces generated by skeletal muscle contractions

Variants in the GLP1R gene (such as rs6923761) affect how your body responds to GLP-1 signaling, while FTO (rs9939609) and MC4R (rs17782313) variants influence metabolic rate and hunger sensation

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To minimize side effects like nausea or fatigue, stay hydrated the day before and eat a small, protein-rich meal

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