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In clinical trials of obese patients, tirzepatide showed even more impressive results in terms of weight loss from baseline, with an average reduction of 20-24%, and in some cases more than 30%, and became the first drug to outperform bariatric surgery (surgical procedures on the stomach and intestines aimed at treating obesity) in terms of effectiveness in studies

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In an interview on the Oprah podcast, Serena opened up about her struggles to lose postpartum weight naturally: "[For] my last match at the Open, I was literally [working out] for eight hours a day in the gym, training, and I never could lose an ounce." She's also shared after taking the drug for a year how "I feel lighter mentally, I feel sexier, I feel more confident" (via Vogue)

Key interconnections include: - Insulin resistance

Efficacy and safety of tirzepatide in patients with type 2 diabetes: a systematic review and meta-analysis