Regulation of desnutrin/ATGL mRNA by glucocorticoids may explain this, since dexamethasone was found to strongly upregulate the enzyme in a concentration- and dose-dependent manner in 3T3-L1 preadipocytes (130)
doi: 10.1073/pnas.2000484117 71 YangQLiMZhaoMLuFYuXLiLet al
It supports the hormonal environment more broadly and is a reason why the best peptides for women approaching perimenopause address multiple systems rather than a single deficiency
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