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Protein carbonyls (PCs) are carbonyl groups embedded in the side chains of amino acids as a result of direct oxidation or reaction with lipid peroxidation products they are a universal indicator of protein damage 47

In ischemiareperfusion injury, which occurs during myocardial infarction, stroke, or following heart transplantation, ferroptosis of endothelial cells and cardiomyocytes releases DAMPs that initiate robust inflammatory responses [167]

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