Transflammation: how innate immune activation and free radicals drive nuclear reprogramming
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At tissue harvest, pancreas samples were fixed in 10% neutral-buffered formalin for 24 h at room temperature and subsequently paraffin-embedded (Leica TP1020 Tissue Processor, Leica Biosystems, Nussloch, Germany) and sectioned at 5 m thickness
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Pivotal clinical trials included few participants over 75, so more research is needed on outcomes as people age
You can read the full article at Effect of Subcutaneous Tirzepatide vs Placebo Added to Titrated Insulin Glargine on Glycemic Control in Patients With Type 2 Diabetes: The SURPASS-5 Randomized Clinical Trial Little is known about the effects of tirzepatide, a medication that stimulates both the glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptors, when added to insulin glargine for treating type 2 diabetes