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The embryonically expressed genes PROP1 (which encodes PROP-1) and POU1F1 (which encodes PIT-1) are involved in pituitary development, including differentiation of pituitary somatotrophic cells

[2] For epilepsy, topiramate should only be used in pregnancy if no suitable alternatives exist, with specialist oversight

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80 :63s65s

may suit larger adults

Clinical trials demonstrate efficacy and safety under controlled conditions