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CAR-T cells mediate major histocompatibility complex (MHC)-unrestricted tumor cell killing by allowing T cells to bind to their cell surface antigens through a scFv recognition domain (151)

Older adults often have a reduced thirst sensation, and GLP-1 medications may further decrease thirst

Contributing Factors: Several factors have contributed to the rise in obesity in Pennsylvania

This observation has raised concerns regarding suboptimal drug exposure, altered pharmacokinetics, and heightened inflammatory burden in obese patients, highlighting the potential need for dose optimization or alternative treatment strategies in this population (63, 64)

This vitamin is unique because it is not synthesized in the body and may only be attained via food sources like Citrus Fruits