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79 The release of mature IL-1 and IL-18 amplifies the inflammatory response in the liver, leading to the recruitment and activation of immune cells, including neutrophils, monocytes, and macrophages

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This inhibition can naturally be thought of as product inhibition, one step removed

The agonist TUG469 ameliorates neurodegeneration and motor impairment both in vitro and in animal models of PD by downregulating the NLR Family Pyrin Domain Containing 3 (NLRP3) inflammasome [66]

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S deposits are typically associated with volcanic regions and hydrothermal vents, where sulfur is precipitated from geothermal fluids [20]