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doi: 10.1007/978-3-319-64804-0_4

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Abstract Immune cells and other cells respond to nutrient deprivation by the classic catabolic pathway of AMPK (Adenosine monophosphate kinase)

Our analysis of The Cancer Genome Atlas (TCGA) human Liver Hepatocellular Carcinoma (LIHC) dataset confirmed that key genes involved in SAA metabolism, including MAT1A , BHMT , CBS , CTH , and CDO1 , are suppressed in HCC compared to normal liver (Supplementary Fig

The economic burden is considerable: annual direct healthcare costs attributable to MASLD in the United States and Europe are estimated in the tens of billions of dollars, driven by hospitalizations, liver-related procedures, and management of comorbid conditions [6]