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The main-chain dihedral angles are well-concentrated in the allowed regions of the Ramachandran plot

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MRTF-A and transcription co-activators YAP/TAZ promotes pathologic and fibroblastic phenotype of the adult human NP cells in association with F-actin stress fibers, indicating that the MRTF-family of co-activators are principal regulators of cytoskeletal dynamics and mechano-sensing, both under normal and diseased physiological conditions

doi: 10.1016/j.cbi.2022.109888