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Furthermore, we identify associations linking variation in both GLP1R and GIPR to GLP1 medication-related nausea or vomiting, with the GIPR association being restricted to people using tirzepatide

Exploration of Drug Science

While Mounjaro was studied primarily in people with type 2 diabetes, some of the strongest evidence for tirzepatide's weight-loss effects comes from dedicated obesity trials

All procedures were approved by the Animal Care and Use Committee of the Shanghai Medical College of Fudan University and were performed according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals

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Do not use GLP-1s if you are pregnant or breastfeeding, or planning to become pregnant or breastfeed