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At the same time, the incidence of diabetic nephropathy, although reduced compared to 20 years ago, is stabilized in recent years, and the incidence of end-stage renal disease (due to reduced cardiovascular mortality and increased life expectancy) is increasing [64]

Future studies should explore more effective combinations of lifestyle interventions and pharmacotherapy, with emphasis on maintaining metabolic health and preserving lean mass, particularly through nutritional support and resistance training, among people at higher risk of sarcopenia

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