International longevity expert Luigi Fontana from the University of Sydney told Four Corners there was no human clinical trial evidence that NAD+ had health or anti-aging benefits, nor was he aware of any safety data
For deliberate weight loss, options with stronger human clinical trial evidence include certain prescription medications (many of which are injectable) and select oral supplements supported by trials
PubChem Compound Summary for CID 9941957 PubChem, Gurtner GC, Werner S, Barrandon Y, Longaker MT
Jastreboff AM, Aronne LJ, Ahmad NN, et al
Ask about common gastrointestinal issues (nausea, vomiting, diarrhea) and rarer risks like gallbladder disease or pancreatitis (FDA Wegovy prescribing information)
A change could make things safer and secure the treatment in the long run