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Both orexin A and orexin B peptides are C-terminally amidated

This review presents an overview of the therapeutic possibilities of six frequently employed DPP4 inhibitors (DPP4is) (Sitagliptin, saxagliptin, vildagliptin, linagliptin, alogliptin and teneligliptin) in managing T2DM, focussing on their characteristics, mechanism of action, advantages and side effects in comparison with alternative oral antidiabetic drugs as well as the possibility of using in silico method in advancing its timely and costeffective production

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It is also known to be closely related to the T2MD metabolic syndrome, and the morbidity and mortality of CVDs (183, 184)

Semaglutide has been associated with cardiovascular benefits, including reduced risk of major adverse cardiovascular events