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State officials acknowledge the drugs work but say they cannot afford to keep paying for them, especially as they brace for federal budget cuts in the coming years

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Semaglutide has been shown to lower appetite, control eating, and minimize food cravings, while also improving glycemic control

Studied together, the pairing has shown meaningful improvements in HbA1c, in insulin resistance markers such as HOMA-IR, and in fat mass over roughly 52 weeks of therapy, which makes it one of the best-established and lowest-risk combinations in modern diabetes care [4]

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Notably, the present narrative review is an extension of a previous review article that covered polyphenols and/or phytoestrogens that included daidzein, equol, genistein, and resveratrol as supplemental therapies for skin aging, which was published in Dermatology and Therapy earlier this year by Lephart (2025) [9]