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290 Activated PARP1 also possesses a transcription-regulatory function, promoting the induction of DNA repair factors by E2F1 and enhancing the progression to treatment-resistant cancer

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For instance, individuals who spend long hours at a desk may find themselves experiencing a dull ache in their lower back or shoulders, often exacerbated by a lack of movement or ergonomic support

doi: 10.21873/cdp.10337 318

18 (Academic Press, 1985)