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These medications work by mimicking the natural incretin hormone GLP-1, which stimulates insulin secretion in response to food intake, suppresses glucagon release, slows gastric emptying, and reduces appetite

Summary Multiple trials clearly demonstrate that SGLT2 inhibitors have beneficial effects on renal function and decrease the development and progression of renal disease (Table 13)

[DOI] [PubMed] [Google Scholar] 19.Katz AS, Goff DC, Feldman SR