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2016, 29, 117-129 DOI: 10.1016/j.ccell.2015.12.008 NMS249 Clin

The impact of growth hormone therapy on sleep-related health outcomes in children with Prader-Willi Syndrome: a review and clinical analysis

The fact that this redox imbalance occurs as a consequence of GSH depletion may explain why several clinical trials have provided no evidence of significant cataract prevention arising from the administration of high dosages of ascorbic acid [13]

These findings indicate that the cerebellar cortical stimulation, which putatively stopped action potential firing in cerebellar nuclei neurons, revealed therapeutic effects on limbic seizures

This has applications in research on insulin resistance, where impaired PI3K/Akt signaling is a key pathological feature, as well as in oncology research, where this pathway is often dysregulated