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Furthermore, the dual inhibition of glutaminase and CPT1 has been shown to reduce the proliferation and migration of CB-839-resistant cells in comparison to the inhibition of individual enzymes
Niu B, Liao K, Zhou Y, Wen T, Quan G, Pan X, et al
Ketogenic diet and ketone bodies enhance the anticancer effects of PD-1 blockade
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Studies suggest this approach can achieve tissue concentrations approaching injectable levels