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GI discomfort: Nausea or stomach upset has been occasionally noted in anecdotal reports

Others find that side effects which were manageable at lower doses become more intrusive

People with a personal or family history of medullary thyroid carcinoma or MEN 2, pregnant or breastfeeding women, people with a history of pancreatitis, severe kidney disease, type 1 diabetes, children and adolescents, people with gastroparesis or severe GI disease, and people with certain unstable cardiovascular conditions

Aryl hydrocarbon receptor activation in chronic kidney disease: role of uremic toxins

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