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doi: 10.1080/15384101.2019.1638190 84 PanXGongNZhaoJYuZGuFChenJet al

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A higher level of oxidative stress and a major imbalance of vasoactive substances (NO and ET-1) was verified in groups IH3 and IH6 (IH6: IH period of 10% O 2 for 15 s followed by a reoxygenation period of 21% O 2 for 3 min and 45 s) [136]

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Early in the course, remyelination of surviving axons can be robust, underpinning clinical remission