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doi: 10.1007/s10545-015-9843-7

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In order to capture this complexity, we have, in collaboration with clinicians and experimentalists, developed mathematical models based on the real underlying physiology [10-16]

First, they help manage blood sugar by signaling the pancreas to release insulin when your blood sugar is high

Notably, metabolic reprogramming has been implicated in the pathological features of fibroblast/myofibroblast activation