Furthermore, the presence of target erythrocytes in the peripheral blood, high levels of lactate dehydrogenase and indirect bilirubin, and morphological changes in bone marrow were the potential clues pointing towards thalassemia
The practical solution: when you get to what you estimate is the last dose in a vial, reconstitute your next vial first and draw the new dose from the fresh vial
Multi-dose vials are generally discouraged in UK practice due to infection control concerns, as outlined in NHS and Specialist Pharmacy Service (SPS) guidance
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