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ROS can enhance the production of these cytokines by activating transcription factors like NF-B and AP-1, creating a feed-forward loop that amplifies inflammation and tissue damage

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In summary, we identified a previously unrecognized human-specific role of -KG in energy sensing by sustaining translation of the energy sensor AMPK

However, the precise impact of aberrant SLC25A39 expression on cellular function in cancer remains unexplored, despite its pivotal role as the primary mitochondrial GSH transporter

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