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Nature (2009) 458(7242):11315

Commonly, tolerance results in a desensitization of GABA receptors

It upregulates genes involved in collagen synthesis (COL1A1, COL3A1, COL5A1), extracellular matrix remodeling (decorin, fibromodulin), and antioxidant defense (superoxide dismutase, glutathione peroxidase) while simultaneously suppressing genes associated with inflammation (IL-6, TNF-alpha), fibrinogen production, and tissue destruction (several MMPs)

The multi-mechanism action of GHK-Cu can enhance results from complementary therapies

Standard dosing ranges from 2-5mg administered subcutaneously two to three times weekly

That calculated risk may be acceptable to consumers, but not to some experts