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JA, SRS, and CJF are supported by funding from the Australian National Health and Medical Research Council

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Combining semaglutide (a GLP-1 receptor agonist) with phentermine (a sympathomimetic) is not FDA-approved as a formal combination, but some providers explore this approach off-label based on differing mechanisms of action

Interestingly, the phospholipid metabolism is also possibly altered by riboflavin deficiency, because PLCA, an enzyme catalyzing the acylation of lysophosphatidic acid to form phosphatidic acid 35 , was up-regulated at the protein expression level in this study