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These potential applications are supported by small RCTs and mechanistic studies indicating ECM remodeling, antioxidant effects, and anti-inflammation [1, 2, 3, 5, 8]

Based on differences in the carbon skeleton, phenolic acids can be mainly divided into two categories: hydroxycinnamic acid (e.g., cinnamic acid, ferulic acid, caffeic acid, and chlorogenic acid) and hydroxybenzoic acid (e.g., gallic acid, ellagic acid, syringic acid, and Danshensu) [157]

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Like a delicate piece of machinery, its effectiveness is entirely dependent on its three-dimensional structure remaining intact

[30] Trazodone is usually administered multiple times per day, but once-daily administration may be similarly effective