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For example, severe neuroinflammation (brain fog) can dysregulate the autonomic nervous system, leading to worsened POTS symptoms (tachycardia), which in turn triggers mast cell degranulation (histamine release)

Trends Immunol 38(1):519 Pinsornsak P, Kanokkangsadal P, Itharat A (2015) The clinical efficacy and safety of the sahastara remedy versus diclofenac in the treatment of osteoarthritis of the knee: a double-blind, randomized, and controlled trial

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doi: 10.1177/1076029620977702 178 MaherP

Cockayne syndrome (CS) genes play important roles in DNA repair and transcription