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Despite their interrelatedness, most research has examined the homocysteine-lowering abilities of folic acid alone, with much less emphasis on B 12 and B 6 and very little attention to B 2

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Moreover, dysregulation of CYP51A1 has been implicated in a wide spectrum of diseases, such as cancer, cataracts, Antley-Bixler syndrome, autoimmune disorders, metabolic liver disease and neurodegeneration

doi: 10.3969/j.issn.1671-0800.2012.10.055 76