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Cell viability assay was performed to examine cytotoxic effects of IL-1, ferrostatin-1 and erastin on ECs

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In addition to high levels of CG methylation, embryonic stem cells also exhibit abundant non-CG methylation in mCHG and mCHH contexts where H=A, C or T (Ramsahoye et al., 2000

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Additionally, the nuclear export signal (NES) in KEAP1 has been shown to be important for NRF2 regulation, as it was found to facilitate the transport of the NRF2-KEAP1 complex out of the nucleus, which terminates NRF2-mediated antioxidant signaling after stress [16]