Patel Chavez, C., Cusi, K
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Some patients report weight loss as early as 2 weeks into the program Clinical effectiveness may vary due to individual factors such as age, weight, diet, exercise, kidney function, and other medical conditions
Vitamin B 12 is essential for three enzymatic processes: the conversion of homocysteine to methionine
This safety profile in animal models provides some reassurance about the compounds fundamental tolerability, though extrapolation to humans requires appropriate caution
The SURMOUNT-4 trial, which tested the maximum tolerated dose approach, showed a mean weight loss of 26% to 26.6% at the highest doses participants could tolerate