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Remarkably, this proinflammatory ATM polarization phenotype was also observed in PAR2-R38E when compared with PAR2-WT mice (Figure 4B and Supplemental Figure 6B)

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Formyl peptide receptor 2 activation ameliorates dermal fibrosis and inflammation in bleomycin-induced scleroderma

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In doing so, the review seeks to offer a structured overview of an under-recognised yet clinically relevant challenge in endocrinology