strong depolarization of the post-synaptic cell completely displaces the magnesium ions that block NMDA ion channels and allows calcium ions to enter a cell probably causing LTP, while weaker depolarization only partially displaces the Mg 2+ ions, resulting in less Ca 2+ entering the post-synaptic neuron and lower intracellular Ca 2+ concentrations (which activate protein phosphatases and induce long-term depression, LTD)
The problem of harmonization as it relates to lesion severity has been recognized and discussed in some detail (Hardisty and Eustis 1990
Glutathione might inhibit the effects of cerebral infarction and enhance antiapoptotic signaling after ischemic stroke, suggesting that GSH may be a potent therapeutic antioxidant that can attenuate severe pathologies after ischemic stroke, and stimulating GSH synthesis through administration of GSH precursors and micronutrients like selenium can optimize GSH and GSH peroxidase for optimal antioxidant defense in cerebral ischemia (155, 156)
Not For Human Or Animal Consumption
Glutathione is a small protein molecule composed of the amino acids glutamate, glycine, and cysteine
The 12mg dose at 120 units (1.20mL) is borderline and can be handled with a single draw using a syringe rated for at least 1.2mL, or a clean 60/60 unit split using two standard syringes
