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10.1038/s41467-017-01328-3 Nat

When you have 2 cysteine molecules coming close to each other, it can oxidize where hydrogens are released from the -SH molecules to form a cystine with disulfide bonds (-S-S-), and this is the form most cysteine molecules will find itself in, although free cysteine residues will also be present

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the relevance to humans remains uncertain and this is not a formal contraindication under current UK/EU labelling

Prescription enzymes should be dosed based on the manufacturers instructions