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Fermentation of fibre by gut microbiota produces short-chain fatty acids, which may stimulate GLP-1 release

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Common schedule: Starting dose: 0.25 mg weekly Increase every 4 weeks Maintenance: up to 2.4 mg (Wegovy) How to take: Same day each week With or without food Injection sites: abdomen, thigh, upper arm Side Effects of Semaglutide Common: Nausea Vomiting Constipation Diarrhea Decreased appetite Monitoring: Patients are monitored for: tolerance weight loss progress overall health Semaglutide vs Tirzepatide Semaglutide targets GLP-1 receptors, while tirzepatide targets both GLP-1 and GIP