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Some clinical trials suggest a neutral effect on arrhythmia risk, indicating that these medications neither significantly increase nor decrease the likelihood of atrial fibrillation

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To optimize the results and to allow patients to experience significant results as quickly as possible, patients will also need to closely follow all other components of their medical weight loss treatment including maintaining a calorie-deficient diet and exercising regularly

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The diuretic effect of spironolactone typically begins within a few days of starting the medication