Convincing improvement in OA In a 2024 paper published in T he New England Journal of Medicine, Bliddal and colleagues enrolled 407 patients with knee OA and obesity in a double-blind, randomized, placebo-controlled trial, called STEP-9, at 61 sites across 11 countries
GLP-1 agonists like semaglutide slow gastric emptying and reduce caloric intake, which directly lowers postprandial (after-meal) triglyceride spikes
Encouragingly, as weight reduces and metabolic health improves, sleep quality often stabilises and may even improve long-term, particularly where weight-related sleep issues existed before treatment
Vitamin B12 is important for synthesizing red blood cells and promoting a healthy nervous system
If you are dehydrated, talk with your doctor
The NHS Eatwell Guide recommends basing meals on starchy carbohydrates (choosing wholegrain where possible) and aiming for at least 30 g of fibre daily from wholegrains, pulses, vegetables, and fruit