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120 There are three subtypes of IDH: IDH1 is located within the cytosol and peroxisomes, and IDH2/3 are primarily found in mitochondria

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The original roGFP versions, roGFP1 and roGFP2, however, have midpoint potentials between 280 and 290 mV rendering them fully oxidized in the ER and almost fully reduced in the cytosol, plastids, mitochondria, and peroxisomes