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While gastrointestinal side effects are the most commonly reported adverse events, long-term studies affirm its overall safety and tolerability

These studies are helpful, but they cannot prove cause and effect

Other benefits reported include lowering cholesterol, weight loss, digestion, fertility and mental health

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Melanotan 2 delivers nanomolar affinities across several melanocortin receptors, while Melanotan 1 shows higher affinity for MC1R, akin to -MSH linked to pigmentation

Annual Review of Biochemistry , 2003