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Topical numbing creams (lidocaine-based) are safe to use before GLP-1 injections and will not affect medication absorption

Suryadevara V, Roy A, Sahoo J, Kamalanathan S, Naik D, Mohan P, et al

Levy also expressed concern that it could cause weight cycling, or yo-yo dieting repeatedly losing and gaining weight, which can have negative health consequences like a higher risk of dying suddenly from a heart attack

Trusted PCOS-Specialized Care *PCOS Sisters membership required What Our Patients Experience Many patients participate in the PCOS Sisters Metabolic Weight Loss Program , which combines GLP-1 medications with lifestyle management and PCOS specific metabolic support

GLP-1, or Glucagon-Like Peptide-1, is a hormone produced in the gut that significantly regulates blood sugar levels and appetite