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insulin is broken down by the stomach acid Concentration the higher the concentration, the more drug that is absorbed (usually!) Ionisation ionised particles cannot diffuse across membranes this plays a part in the mechanism of action for local anaesthetics Solubility drugs that are more polar (see below) are less readily absorbed through the lipid bilayer of the cell membrane Physical state of the drug e.g

Phospholipid Complex (from Lecithin): Lecithin which is rich in phospholipids, is like a delivery system which allows Glutathione to be absorbed effectively by bodys cells, contributing targeted cellular delivery, high bioavailability, enhanced brain health and optimal cellular function

Despite advancements in conventional treatments, including targeted therapies for aggressive types like ATC and MTC, integrating plant-based compounds remains a promising area of research

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