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In summary, the key interactions to consider are pyridoxines reduction of levodopa and anticonvulsant efficacy, niacinamides additive effects on blood pressure, blood sugar, and gout management, and the potential need for B-vitamin repletion in patients on certain medications (diuretics, isoniazid, etc.)

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doi: 10.1016/j.jand.2019.10.013, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 26.Mohan A, Kumar R, Kumar V, Yadav M

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