[DOI] [PubMed] [Google Scholar] 122.Lubos E., Loscalzo J., Handy D.E
, & Jessop, D
Common adverse effects of GLP-1 receptor agonists include: Gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation)usually mild to moderate and often diminishing over time Injection site reactions Headache Fatigue More serious but rare adverse effects have been identified, including: Pancreatitis patients should seek urgent medical advice for severe, persistent abdominal pain (with or without vomiting) Gallbladder disease symptoms include upper right abdominal pain and jaundice Diabetic retinopathy complications particularly with rapid HbA1c reduction in patients with pre-existing retinopathy Dehydration and acute kidney injury from persistent gastrointestinal symptoms When combined with sulfonylureas or insulin, GLP-1 receptor agonists increase the risk of hypoglycaemia
It also promises a positive impact on digestion, creating a lifestyle where healthier living is sustainable and uncomplicated
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A recent comparative study indicated that PEG-coated Au NPs induced less hepatotoxic outcomes than uncoated Au NPs in Sprague Dawley rats, which showed that PEG-coated Au NPs might be safer for biomedical applications (Patlolla et al., 2019)