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Biochemical dysfunction discussed here include mitochondrial dysfunction [62,63,64] (such as adenosine triphosphate (ATP) production) [37, 65,66,67,68,69], impaired biochemical pathways (the kynurenine pathway [70,71,72,73] and the itaconate shunt [74,75,76,77]), chemical composition of cells (Raman spectroscopy [33, 58, 78] and metabolomic analysis [79,80,81]), and the production of cytokines [47,48,49]

Dosing range: 250-500mcg subcutaneous once daily

9 Dietary and Lifestyle Considerations Diet and Exercise Mediterranean diet

Aim for at least 2 to 3 liters of water daily

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It calms the immune system and reduces proinflammatory factors