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The Bottom Line: Compared with other GLP-1 RAs, Ozempic is a strong A1c reducer with the added benefits of moderate weight loss and possible cardiovascular protection

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None of the approved GLP-1 or dual-agonist products carries a dermatologic indication, and the largest relevant real-world study, a target trial emulation with matched cohorts of 169,630 each, found no significant differences for inflammatory or autoimmune skin outcomes other than psoriasis, pemphigus and bullous pemphigoid after correction for multiple testing