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High gastrointestinal absorption is desirable for XO inhibitors intended for systemic therapeutic action, such as in the treatment of gout

Figure 2 shows that the biphasic PK profile obtained from the two-compartment model is consistent with intravenous data and, furthermore, that the rate of absorption as well as the maximum concentration following subcutaneous doses of different strengths were well captured by the model

JAMA Netw Open 5(9):e2231982e2231982 Gao X et al (2022) Efficacy and safety of semaglutide on weight loss in obese or overweight patients without diabetes: a systematic review and meta-analysis of randomized controlled trials

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Gestational hypoxia and developmental plasticity