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Specifically, in diabetes, elevated glucose levels increase ROS production via the PI3K/AKT signaling pathway, aggravating oxidative stress in the ocular surface, damaging the epithelium cells, and affecting tear film stability, thereby leading to DED (Lu et al., 2018

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Rosenstock J, Brazg R, Andryuk PJ, et al

The article suggests your endocrinologist or primary care provider then review whether the steroid is necessary, whether a lower dose or shorter duration would suffice, and whether an alternative anti-inflammatory agent could reduce interaction risk

If you or your weight management doctor raise concerns about side effects, ask about ways to minimize them, such as starting with a lower dose or adjusting your diet